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Errates and Retraction Notes

#932337

25 Mar 2021 : Retraction note  

Retracted: Mukonal Inhibits Cell Proliferation, Alters Mitochondrial Membrane Potential and Induces Apoptosis and Autophagy in Human CNE1 Nasopharyngeal Carcinoma Cells

Yingyuan Guo, Yanru Hao [...]

DOI: 10.12659/MSM.932337

Med Sci Monit 2021; 27:e932337

#932337

25 Mar 2021 : Retraction note  

Retracted: Mukonal Inhibits Cell Proliferation, Alters Mitochondrial Membrane Potential and Induces Apoptosis and Autophagy in Human CNE1 Nasopharyngeal Carcinoma Cells

Yingyuan Guo, Yanru Hao, Guofang Guan, Shuaishuai Ma, Zhiling Zhu, Fang Guo, Jie Bai

DOI: 10.12659/MSM.932337

Med Sci Monit 2021; 27:e932337

2,997

#932335

25 Mar 2021 : Retraction note  

Retracted: Morusinol Exhibits Selective and Potent Antitumor Activity Against Human Liver Carcinoma by Inducing Autophagy, G2/M Cell Cycle Arrest, Inhibition of Cell Invasion and Migration, and Targeting of Ras/MEK/ERK Pathway

Zhen Zhu, Tianyu Xiao [...]

DOI: 10.12659/MSM.932335

Med Sci Monit 2021; 27:e932335

#932335

25 Mar 2021 : Retraction note  

Retracted: Morusinol Exhibits Selective and Potent Antitumor Activity Against Human Liver Carcinoma by Inducing Autophagy, G2/M Cell Cycle Arrest, Inhibition of Cell Invasion and Migration, and Targeting of Ras/MEK/ERK Pathway

Zhen Zhu, Tianyu Xiao, Xuejiao Chang, Yanfei Hua, Jinli Gao

DOI: 10.12659/MSM.932335

Med Sci Monit 2021; 27:e932335

2,892

#932333

25 Mar 2021 : Retraction note  

Retracted: Phillygenin Exerts In Vitro and In Vivo Antitumor Effects in Drug-Resistant Human Esophageal Cancer Cells by Inducing Mitochondrial-Mediated Apoptosis, ROS Generation, and Inhibition of the Nuclear Factor kappa B NF-κB Signalling Pathway

Jiantao He, Wei Wei [...]

DOI: 10.12659/MSM.932333

Med Sci Monit 2021; 27:e932333

#932333

25 Mar 2021 : Retraction note  

Retracted: Phillygenin Exerts In Vitro and In Vivo Antitumor Effects in Drug-Resistant Human Esophageal Cancer Cells by Inducing Mitochondrial-Mediated Apoptosis, ROS Generation, and Inhibition of the Nuclear Factor kappa B NF-κB Signalling Pathway

Jiantao He, Wei Wei, Qingbo Yang, Yiling Wang

DOI: 10.12659/MSM.932333

Med Sci Monit 2021; 27:e932333

2,950

#932332

25 Mar 2021 : Retraction note  

Retracted: Taxol-Resistant Gene 1 (Txr1) Mediates Oxaliplatin Resistance by Inducing Autophagy in Human Nasopharyngeal Carcinoma Cells

Hua-ming Chi, Jing-dong Du [...]

DOI: 10.12659/MSM.932332

Med Sci Monit 2021; 27:e932332

#932332

25 Mar 2021 : Retraction note  

Retracted: Taxol-Resistant Gene 1 (Txr1) Mediates Oxaliplatin Resistance by Inducing Autophagy in Human Nasopharyngeal Carcinoma Cells

Hua-ming Chi, Jing-dong Du, Jie Cheng, Hua-dong Mao

DOI: 10.12659/MSM.932332

Med Sci Monit 2021; 27:e932332

2,678

#932331

25 Mar 2021 : Retraction note  

Retracted: Anticancer Activity of Metformin, an Antidiabetic Drug, Against Ovarian Cancer Cells Involves Inhibition of Cysteine-Rich 61 (Cyr61)/Akt/Mammalian Target of Rapamycin (mTOR) Signaling Pathway

Fengli Zhang, Huixiao Chen [...]

DOI: 10.12659/MSM.932331

Med Sci Monit 2021; 27:e932331

#932331

25 Mar 2021 : Retraction note  

Retracted: Anticancer Activity of Metformin, an Antidiabetic Drug, Against Ovarian Cancer Cells Involves Inhibition of Cysteine-Rich 61 (Cyr61)/Akt/Mammalian Target of Rapamycin (mTOR) Signaling Pathway

Fengli Zhang, Huixiao Chen, Jing Du, Bin Wang, Lixiao Yang

DOI: 10.12659/MSM.932331

Med Sci Monit 2021; 27:e932331

2,913

#932328

25 Mar 2021 : Retraction note  

Retracted: Effects of 3-Tetrazolyl Methyl-3-Hydroxy-Oxindole Hybrid (THOH) on Cell Proliferation, Apoptosis, and G2/M Cell Cycle Arrest Occurs by Targeting Platelet-Derived Growth Factor D (PDGF-D) and the MEK/ERK Signaling Pathway in Human Lung Cell Lines SK-LU-1, A549, and A-427

Peng Li, Zhiqiang Zhang [...]

DOI: 10.12659/MSM.932328

Med Sci Monit 2021; 27:e932328

#932328

25 Mar 2021 : Retraction note  

Retracted: Effects of 3-Tetrazolyl Methyl-3-Hydroxy-Oxindole Hybrid (THOH) on Cell Proliferation, Apoptosis, and G2/M Cell Cycle Arrest Occurs by Targeting Platelet-Derived Growth Factor D (PDGF-D) and the MEK/ERK Signaling Pathway in Human Lung Cell Lines SK-LU-1, A549, and A-427

Peng Li, Zhiqiang Zhang, Feng Zhang, Hongling Zhou, Bei Sun

DOI: 10.12659/MSM.932328

Med Sci Monit 2021; 27:e932328

3,814

#932330

25 Mar 2021 : Retraction note  

Retracted: Evodiamine Induces Apoptosis, G2/M Cell Cycle Arrest, and Inhibition of Cell Migration and Invasion in Human Osteosarcoma Cells via Raf/MEK/ERK Signalling Pathway

Yuelai Zhou, Jinlong Hu

DOI: 10.12659/MSM.932330

Med Sci Monit 2021; 27:e932330

#932330

25 Mar 2021 : Retraction note  

Retracted: Evodiamine Induces Apoptosis, G2/M Cell Cycle Arrest, and Inhibition of Cell Migration and Invasion in Human Osteosarcoma Cells via Raf/MEK/ERK Signalling Pathway

Yuelai Zhou, Jinlong Hu

DOI: 10.12659/MSM.932330

Med Sci Monit 2021; 27:e932330

3,103

#932341

25 Mar 2021 : Retraction note  

Retracted: Ferruginol Diterpenoid Selectively Inhibits Human Thyroid Cancer Growth by Inducing Mitochondrial Dependent Apoptosis, Endogenous Reactive Oxygen Species (ROS) Production, Mitochondrial Membrane Potential Loss and Suppression of Mitogen-Activated Protein Kinase (MAPK) and PI3K/AKT Signaling Pathways

Guoqing Luo, Jingjing Zhou [...]

DOI: 10.12659/MSM.932341

Med Sci Monit 2021; 27:e932341

#932341

25 Mar 2021 : Retraction note  

Retracted: Ferruginol Diterpenoid Selectively Inhibits Human Thyroid Cancer Growth by Inducing Mitochondrial Dependent Apoptosis, Endogenous Reactive Oxygen Species (ROS) Production, Mitochondrial Membrane Potential Loss and Suppression of Mitogen-Activated Protein Kinase (MAPK) and PI3K/AKT Signaling Pathways

Guoqing Luo, Jingjing Zhou, Guanjie Li, Ningdong Hu, Xu Xia, Haibo Zhou

DOI: 10.12659/MSM.932341

Med Sci Monit 2021; 27:e932341

4,101

#932092

17 Mar 2021 : Retraction note  

Retracted: Autopsy and Histologic Findings of Patients with New Coronavirus Pneumonia: The Pathologic Associations with Hypoxemia

Heng Zhang, Jun Zhou [...]

DOI: 10.12659/MSM.932092

Med Sci Monit 2021; 27:e932092

#932092

17 Mar 2021 : Retraction note  

Retracted: Autopsy and Histologic Findings of Patients with New Coronavirus Pneumonia: The Pathologic Associations with Hypoxemia

Heng Zhang, Jun Zhou, Rong Chen, Yong Ren, Jun Cai, Lei Zhao, Xiaochun Fei, Zhenhua Liu, Yu Zhang, Ling Yuan, Chaofu Wang

DOI: 10.12659/MSM.932092

Med Sci Monit 2021; 27:e932092

5,274

#931623

11 Mar 2021 : Retraction note  

Retracted: Inhibition of Nasopharyngeal Carcinoma by Beta-Lapachone Occurs by Targeting the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Pathway, Reactive Oxygen Species (ROS) Production, and Autophagy Induction

Yongqing Han, Dayou Shi [...]

DOI: 10.12659/MSM.931623

Med Sci Monit 2021; 27:e931623

#931623

11 Mar 2021 : Retraction note  

Retracted: Inhibition of Nasopharyngeal Carcinoma by Beta-Lapachone Occurs by Targeting the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Pathway, Reactive Oxygen Species (ROS) Production, and Autophagy Induction

Yongqing Han, Dayou Shi, Jingao Li

DOI: 10.12659/MSM.931623

Med Sci Monit 2021; 27:e931623

3,560

#931590

11 Mar 2021 : Retraction note  

Retracted: The Effects of Ludartin on Cell Proliferation, Cell Migration, Cell Cycle Arrest and Apoptosis Are Associated with Upregulation of p21WAF1 in Saos-2 Osteosarcoma Cells In Vitro

Shuang-li Zhang, Bao-lin Li [...]

DOI: 10.12659/MSM.931590

Med Sci Monit 2021; 27:e931590

#931590

11 Mar 2021 : Retraction note  

Retracted: The Effects of Ludartin on Cell Proliferation, Cell Migration, Cell Cycle Arrest and Apoptosis Are Associated with Upregulation of p21WAF1 in Saos-2 Osteosarcoma Cells In Vitro

Shuang-li Zhang, Bao-lin Li, Wei Li, Ming Lu, Lin-ying Ni, Hui-li Ma, Qing-gang Meng

DOI: 10.12659/MSM.931590

Med Sci Monit 2021; 27:e931590

2,722

#931280

11 Mar 2021 : Retraction note  

Retracted: Protective Effect of Circular RNA (CircRNA) Ddx17 in Ovalbumin (OVA)-Induced Allergic Rhinitis (AR) Mice

Jiao Liu, Zhiwei Cao

DOI: 10.12659/MSM.931280

Med Sci Monit 2021; 27:e931280

#931280

11 Mar 2021 : Retraction note  

Retracted: Protective Effect of Circular RNA (CircRNA) Ddx17 in Ovalbumin (OVA)-Induced Allergic Rhinitis (AR) Mice

Jiao Liu, Zhiwei Cao

DOI: 10.12659/MSM.931280

Med Sci Monit 2021; 27:e931280

4,181

#931225

11 Mar 2021 : Retraction note  

Retracted: Girinimbine Inhibits the Proliferation of Human Ovarian Cancer Cells In Vitro via the Phosphatidylinositol-3-Kinase (PI3K)/Akt and the Mammalian Target of Rapamycin (mTOR) and Wnt/β-Catenin Signaling Pathways

Qiu Xin, An Muer

DOI: 10.12659/MSM.931225

Med Sci Monit 2021; 27:e931225

#931225

11 Mar 2021 : Retraction note  

Retracted: Girinimbine Inhibits the Proliferation of Human Ovarian Cancer Cells In Vitro via the Phosphatidylinositol-3-Kinase (PI3K)/Akt and the Mammalian Target of Rapamycin (mTOR) and Wnt/β-Catenin Signaling Pathways

Qiu Xin, An Muer

DOI: 10.12659/MSM.931225

Med Sci Monit 2021; 27:e931225

2,994

#931025

11 Mar 2021 : Retraction note  

Retracted: Parthenolide Inhibits the Proliferation of MDA-T32 Papillary Thyroid Carcinoma Cells In Vitro and in Mouse Tumor Xenografts and Activates Autophagy and Apoptosis by Downregulation of the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Signaling Pathway

Chao Li, Yuqiu Zhou [...]

DOI: 10.12659/MSM.931025

Med Sci Monit 2021; 27:e931025

#931025

11 Mar 2021 : Retraction note  

Retracted: Parthenolide Inhibits the Proliferation of MDA-T32 Papillary Thyroid Carcinoma Cells In Vitro and in Mouse Tumor Xenografts and Activates Autophagy and Apoptosis by Downregulation of the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Signaling Pathway

Chao Li, Yuqiu Zhou, Yongcong Cai, Chunyan Shui, Wei Liu, Xu Wang, Jian Jiang, Dingfen Zeng, Chunhan Gui, Ronghao Sun

DOI: 10.12659/MSM.931025

Med Sci Monit 2021; 27:e931025

3,423

#931024

28 Jan 2021 : Retraction note  

Retracted: Dexmedetomidine Regulates Proliferation, Apoptosis, Migration, and Invasion in Ovarian Cancer Cells via MiR-155-HIF-1α Axis

Lihong Zheng, Ruimei Jia [...]

DOI: 10.12659/MSM.931024

Med Sci Monit 2021; 27:e931024

#931024

28 Jan 2021 : Retraction note  

Retracted: Dexmedetomidine Regulates Proliferation, Apoptosis, Migration, and Invasion in Ovarian Cancer Cells via MiR-155-HIF-1α Axis

Lihong Zheng, Ruimei Jia, Juan Zhao

DOI: 10.12659/MSM.931024

Med Sci Monit 2021; 27:e931024

2,757

#930778

21 Jan 2021 : Retraction note  

Retracted: Pleuromutilin Inhibits Proliferation and Migration of A2780 and Caov-3 Ovarian Carcinoma Cells and Growth of Mouse A2780 Tumor Xenografts by Down-Regulation of pFAK2

Bo Zhang, Xiaoli Ma [...]

DOI: 10.12659/MSM.930778

Med Sci Monit 2021; 27:e930778

#930778

21 Jan 2021 : Retraction note  

Retracted: Pleuromutilin Inhibits Proliferation and Migration of A2780 and Caov-3 Ovarian Carcinoma Cells and Growth of Mouse A2780 Tumor Xenografts by Down-Regulation of pFAK2

Bo Zhang, Xiaoli Ma, Yuan Li, Sijing Li, Jiumei Cheng

DOI: 10.12659/MSM.930778

Med Sci Monit 2021; 27:e930778

3,208

#930758

16 Jan 2021 : Retraction note  

Retracted: Ursolic Acid Exhibits Potent Anticancer Effects in Human Metastatic Melanoma Cancer Cells (SK-MEL-24) via Apoptosis Induction, Inhibition of Cell Migration and Invasion, Cell Cycle Arrest, and Inhibition of Mitogen-Activated Protein Kinase (MAPK)/ERK Signaling Pathway

Pengcheng Liu, Ruili Du [...]

DOI: 10.12659/MSM.930758

Med Sci Monit 2021; 27:e930758

#930758

16 Jan 2021 : Retraction note  

Retracted: Ursolic Acid Exhibits Potent Anticancer Effects in Human Metastatic Melanoma Cancer Cells (SK-MEL-24) via Apoptosis Induction, Inhibition of Cell Migration and Invasion, Cell Cycle Arrest, and Inhibition of Mitogen-Activated Protein Kinase (MAPK)/ERK Signaling Pathway

Pengcheng Liu, Ruili Du, Xin Yu

DOI: 10.12659/MSM.930758

Med Sci Monit 2021; 27:e930758

2,583

#930755

30 Dec 2020 : Retraction note  

Retracted: Naturally Occurring Sesquiterpene Lactone-Santonin, Exerts Anticancer Effects in Multi-Drug Resistant Breast Cancer Cells by Inducing Mitochondrial Mediated Apoptosis, Caspase Activation, Cell Cycle Arrest, and by Targeting Ras/Raf/MEK/ERK Signaling Pathway

Zhiqiang Wu, Chenchen Wang [...]

DOI: 10.12659/MSM.930755

Med Sci Monit 2020; 26:e930755

#930755

30 Dec 2020 : Retraction note  

Retracted: Naturally Occurring Sesquiterpene Lactone-Santonin, Exerts Anticancer Effects in Multi-Drug Resistant Breast Cancer Cells by Inducing Mitochondrial Mediated Apoptosis, Caspase Activation, Cell Cycle Arrest, and by Targeting Ras/Raf/MEK/ERK Signaling Pathway

Zhiqiang Wu, Chenchen Wang, Mingzhu Huang, Zhonghua Tao, Wangjun Yan, Yiqun Du

DOI: 10.12659/MSM.930755

Med Sci Monit 2020; 26:e930755

1,939

#929638

15 Nov 2020 : Errate  

Erratum: MicroRNA-125b Down-Regulation Mediates Endometrial Cancer Invasion by Targeting ERBB2

Chao Shang, Yan-ming Lu [...]

DOI: 10.12659/MSM.929638

Med Sci Monit 2020; 26:e929638

#929638

15 Nov 2020 : Errate  

Erratum: MicroRNA-125b Down-Regulation Mediates Endometrial Cancer Invasion by Targeting ERBB2

Chao Shang, Yan-ming Lu, Li-rong Meng

DOI: 10.12659/MSM.929638

Med Sci Monit 2020; 26:e929638

2,430

#927410

21 Sep 2020 : Errate  

Erratum: Long Noncoding RNA (lncRNA) Maternally Expressed Gene 3 (MEG3) Participates in Chronic Obstructive Pulmonary Disease through Regulating Human Pulmonary Microvascular Endothelial Cell Apoptosis

Hui Bi, Gui Wang [...]

DOI: 10.12659/MSM.927410

Med Sci Monit 2020; 26:e927410

#927410

21 Sep 2020 : Errate  

Erratum: Long Noncoding RNA (lncRNA) Maternally Expressed Gene 3 (MEG3) Participates in Chronic Obstructive Pulmonary Disease through Regulating Human Pulmonary Microvascular Endothelial Cell Apoptosis

Hui Bi, Gui Wang, Zhiying Li, Lin Zhou, Ming Zhang, Jiru Ye, Zhigang Wang

DOI: 10.12659/MSM.927410

Med Sci Monit 2020; 26:e927410

2,542

#926434

16 Jun 2020 : Errate  

Erratum: Measurement of the Combined Levels of Serum Uric Acid and Alanine Aminotransferase and the Risk of Metabolic Syndrome in a Population Aged 60 Years or More in Northeastern China

Jiabei Wang, Yingfang Wang [...]

DOI: 10.12659/MSM.926434

Med Sci Monit 2020; 26:e926434

#926434

16 Jun 2020 : Errate  

Erratum: Measurement of the Combined Levels of Serum Uric Acid and Alanine Aminotransferase and the Risk of Metabolic Syndrome in a Population Aged 60 Years or More in Northeastern China

Jiabei Wang, Yingfang Wang, Feng Chen, Guojing Ma, Difei Wang

DOI: 10.12659/MSM.926434

Med Sci Monit 2020; 26:e926434

1,907

#926333

12 Jun 2020 : Errate  

Erratum: Multifunctional Polyethylene Glycol (PEG)-Poly (Lactic-Co-Glycolic Acid) (PLGA)-Based Nanoparticles Loading Doxorubicin and Tetrahydrocurcumin for Combined Chemoradiotherapy of Glioma

Xingzhen Zhang, Lixia Zhao [...]

DOI: 10.12659/MSM.926333

Med Sci Monit 2020; 26:e926333

#926333

12 Jun 2020 : Errate  

Erratum: Multifunctional Polyethylene Glycol (PEG)-Poly (Lactic-Co-Glycolic Acid) (PLGA)-Based Nanoparticles Loading Doxorubicin and Tetrahydrocurcumin for Combined Chemoradiotherapy of Glioma

Xingzhen Zhang, Lixia Zhao, Guangxi Zhai, Jianbo Ji, Anchang Liu

DOI: 10.12659/MSM.926333

Med Sci Monit 2020; 26:e926333

1,554

#926160

09 Jun 2020 : Errate  

Erratum: The p66shc-Mediated Regulation of Hepatocyte Senescence Influences Hepatic Steatosis in Nonalcoholic Fatty Liver Disease

Jing Zhang, Yanpeng Li [...]

DOI: 10.12659/MSM.926160

Med Sci Monit 2020; 26:e926160

#926160

09 Jun 2020 : Errate  

Erratum: The p66shc-Mediated Regulation of Hepatocyte Senescence Influences Hepatic Steatosis in Nonalcoholic Fatty Liver Disease

Jing Zhang, Yanpeng Li, Bingyuan Wang, Yan Luo, Junping Shi, Baiyun Zhao

DOI: 10.12659/MSM.926160

Med Sci Monit 2020; 26:e926160

1,606

#924162

11 Apr 2020 : Errate  

Erratum: Upregulation of miR-9 Target CBX7 Regulates Invasion Ability of Bladder Transitional Cell Carcinoma

Dalong Xie, Chao Shang [...]

DOI: 10.12659/MSM.924162

Med Sci Monit 2020; 26:e924162

#924162

11 Apr 2020 : Errate  

Erratum: Upregulation of miR-9 Target CBX7 Regulates Invasion Ability of Bladder Transitional Cell Carcinoma

Dalong Xie, Chao Shang, Hui Zhang, Yan Guo, Xiaojie Tong

DOI: 10.12659/MSM.924162

Med Sci Monit 2020; 26:e924162

1,606

#923878

10 Apr 2020 : Errate  

Erratum: Association of 3 Common Polymorphisms of IL-27 Gene with Susceptibility to Cancer in Chinese People: Evidence from an Updated Meta-Analysis of 27 Studies

Meng Zhang, Xiuxiu Tan [...]

DOI: 10.12659/MSM.923878

Med Sci Monit 2020; 26:e923878

#923878

10 Apr 2020 : Errate  

Erratum: Association of 3 Common Polymorphisms of IL-27 Gene with Susceptibility to Cancer in Chinese People: Evidence from an Updated Meta-Analysis of 27 Studies

Meng Zhang, Xiuxiu Tan, Junjie Huang, Zekai Ke, Yukun Ge, Hu Xiong, Wei Lu, Lu Fang, Zhiming Cai, Song Wu

DOI: 10.12659/MSM.923878

Med Sci Monit 2020; 26:e923878

1,693

Editorial

01 January 2026 : Editorial  

Editorial: Increasing Awareness of Lung Cancer in Non-Smokers and Never-Smokers Challenges Current Approaches to Prevention and Screening

Dinah V. Parums ORCID logo

DOI: 10.12659/MSM.952454

Med Sci Monit 2026; 32:e952454

0:00

In Press

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Institutional and Regional Variations in Access to Clinical Trials and Next-Generation Sequencing in Turkis...

Med Sci Monit In Press; DOI: 10.12659/MSM.951027  

Clinical Research  

Low-Intensity Blood Flow-Restricted Multi-Joint Exercise Improves Muscle Function in Patients With Patellof...

Med Sci Monit In Press; DOI: 10.12659/MSM.950516  

Review article  

Musculoskeletal Ultrasound and MRI in the Evaluation of Chemotherapy-Induced Peripheral Neuropathy: A Review

Med Sci Monit In Press; DOI: 10.12659/MSM.951283  

Clinical Research  

Sensory Processing, Dissociation, and Affective Symptoms in Misophonia: A Cross-Sectional Study of 35 Adults

Med Sci Monit In Press; DOI: 10.12659/MSM.950938  

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Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

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13 Nov 2021 : Clinical Research   3,708,487

Acceptance of COVID-19 Vaccination and Its Associated Factors Among Cancer Patients Attending the Oncology ...

DOI :10.12659/MSM.932788

Med Sci Monit 2021; 27:e932788

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14 Dec 2022 : Clinical Research   2,341,643

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

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16 May 2023 : Clinical Research   706,524

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750